Monday, January 02, 2012

DHEA Protocol

“Magnesium chloride, especially when applied transdermally, can gradually increase DHEA in a natural way” Dr. Norman Shealy

“It is commonly reported that decreasing DHEA levels are inevitable with aging. But I have seen healthy, active eighty-year-olds with optimal DHEA levels and I have seen stressed-out thirty-year-olds with low or deficient levels of DHEA. Very low DHEA levels often precede a major illness by several years. Insulin, blood sugar, and cortisone all cause increased secretion of DHEA into urine. Prolonged stress, which may raise insulin, blood sugar and cortisol, eventually leads to low DHEA blood levels.”  Doctor Norman Shealy

“DHEA has been shown to possess multitargeted antioxidant activity, including effectiveness against glucose-induced lipid peroxidation. This protects the kidneys against oxidative damage and impairment of cell growth, suggesting effectiveness in overcoming chronic renal complications associated with diabetes.” Brighardello et al 2000

“Animal studies indicate that DHEA may have chemopreventive effects (5) (6), may
block the development of tumors (7) and enhance immune response following hepatitis (8) and influenza (9) vaccinations. DHEA may play a role in increasing immune response in acquired immune deficiency syndrome (AIDS) (2). In clinical trials, DHEA has been shown to be effective in treating major depression (10), schizophrenia induced anxiety (11), systematic lupus erythematosus (12), osteoporosis (13), erectile dysfunction (14) and Addison's disease (15) (16) (17) (16) (18).” Memorial Sloan-Kettering Cancer Center

“DHEA is a major marker for age and health. Its major effect in a coping person is anti-stress, meaning that the increased cortisone produced by stress is subsequently normally brought back down to baseline by a rise in DHEA.” Doctor Norman Shealy

“Decreases in DHEA levels have been linked to a number of chronic and degenerative diseases including cancer, coronary artery disease, depression, stress disorders and neurological dysfunctioning.” Straub et al

“DHEA-S may have substantial therapeutic benefits for the treatment of ischemic
 stroke.” Lapchak et al 2000

“Levels of estradiol were higher and levels of DHEA were lower in rheumatoid arthritis patients compared to subjects not suffering from chronic inflammation.” Tengstrand et al

“In animal models pregnenolone and DHEA have been shown to profoundly stimulate the healing of neurologic injury.” Li H et al 

“Individuals with macular degeneration tend to have low blood levels of the hormone DHEA as well as a higher risk of cardiovascular mortality.” Life Extension

“DHEA is the most abundant of all steroids and is released from the adrenal glands. DHEA is involved in the manufacturing of testosterone, estrogen, progesterone and corticosteroids. The decline of DHEA parallels that of growth hormone. By age 65, the body makes only 10-20% of DHEA that was made at age 20. It has been shown in animal studies to act as an agent of anti-obesity, anti-cancer, anti-autoimmune disease, anti-stress, anti-infectious disease. In other words, it is an all around anti-aging drug. It may also boost the function of the brain as the brain tissue contains 6 times more DHEA than any other tissue in the body.”  Doctor Michael Lam MD

"DHEA appears to exert a positive role in bone metabolism by inhibiting bone resorption and stimulating bone formation. It also seems to aid calcium absorption. DHEA has proved effective in clinical trials treating osteoporosis. However, a correlation between DHEA and bone mineral density appears variably in women and not at all in men." Life Extension

Levels of DHEA and DHEA-s in older men strongly predict death by CVD."  Doctor Claes Ohlsson University of Gothenburg


DHEA Hormone Feedstock

"Prof. Shulman found that women being treated for infertility who also received supplements of DHEA were three times more likely to conceive than women being treated without the additional drug. The results were recently published in AYALA, the journal of the Israeli Fertility Association.”    DHEA for Infertility, Note this is demonstrating just how important DHEA is for ANY hormone related problem


DHEA or dehyroepiandrosterone is a natural steroid hormone secreted by the adrenal gland, gonads and your brain. DHEA is a key testosterone (See Testosterone Protocol) estrogen and other steroids precursor, produced naturally by your body. As you get older your DHEA levels usually begin to rapidly decline. By the time you reach 40 your DHEA level has fallen to less than half of its levels when you were 20; by 60 it will typically be 1/4. DHEA helps boost your testosterone levels; your bone strength, proper insulin balance and helps keep your weight (See Overweight Protocol) good among other good things. Cholesterol is the feedstock your body uses to manufacture DHEA so you want to assure its supply. Women and men who are having problems with their bones should have their DHEA levels checked as a low DHEA level can result in as much as a 40-fold increase in your risk of osteoporosis. 


Youthful DHEA levels help

  • Reduce risk of many diseases including cancer, cardiovascular and diabetes
  • Reduce inflammation
  • Reduce stress levels
  • Reduce bone loss
  • Reduce Cancer proliferation
  • Reduce depression
  • Reduce stress
  • Reduce effective aging
  • Reduce viral loads
  • Increase bone formation
  • Increase hormone availability
  • Increase immune response
  • Increase perceptions of physical and psychological well-being
  • Maintain skin
  • Maintain bone
  • Maintain memory
  • Maintain nerves
  • Maintain brain
  • Maintain heart
  • Maintain vascular system
  • Maintain proper weight
  • Balance Insulin
  • Build muscle

“Magnesium chloride, especially when applied transdermally, is reported by Doctor Norman Shealy to gradually increase DHEA in a natural way. Doctor Shealy has determined that when the body is presented with adequate levels of magnesium at the cellular level, the body will begin to naturally produce DHEA and also DHEA-S. Because of the problems with supplementing directly with DHEA, transdermal magnesium chloride mineral therapy holds great promise for DHEA hormonal supplementation because taking magnesium could counteract the heart attack and stroke hazards of synthetic DHEA hormone replacement therapy.” Magnesium for Life Mark Sircus

Through the use of Magnesium Oil, women have reported complete abatement of menopausal symptoms and some have even returned to their menstrual cycle and the possible explanation for this is that rising magnesium levels brings up DHEA levels.


Avoid for optimal DHEA levels


To Increase DHEA


Be sure to consult your doctor before taking supplemental DHEA. Have your levels checked; youthful DHEA levels fall between 300 and 500 mcg/dl. If you discover your levels are low, discuss with your doctor the best supplemental dosage and the optimum DHEA level you want. IMO always seriously attempt to raise your DHEA levels naturally for a good six months before using supplemental DHEA.


IMO it is VERY important to use every means to bring up your DHEA levels after you pass 40 or so.

Be very careful with DHEA supplements however they may shut down your body’s natural DHEA production. Also by supplementing DHEA it’s possible to get too high a blood level of DHEA which may cause you no end of serious problems. IMO find a good integrative doctor to help and test your levels if you must supplement DHEA.

DHEA is so important for so many functions IMO it’s worth the effort to try and get your body to produce more DHEA. Magnesium chloride oil seems to be the best way to do this but I use them all. I use transdermal Magnesium Chloride oil, HGH, exercise and every other indirect method to attempt to raise my DHEA levels.

Caution: Do not take this or any other hormone (See Hormone Supplements Protocol) without researching hormone supplementation and having your levels checked. In particular do not take supplemental hormones if under the age of about forty. It is strongly suggested you consult with a knowledgeable Integrative Doctor on hormone supplementation. Women especially should consult a  knowledgeable Integrative Doctor on DHEA and all hormone supplementation. EXCEPTIONS: Women with breast, uterine, or ovarian cancer or men with prostate cancer should not take supplemental DHEA.


DHEA can be used Short Term Episodically to Boost Immunity

The administration of 50 mg a day of DHEA to elderly men resulted in the following immune enhancements compared to placebo. YOU only want to do this in a life threatening situation IMO.

  • Increase of 35% in the number of monocyte immune cells
  • Increase of 29% in the number of B immune cells
  • Increase of 62% in B-cell activity
  • Increase of 40% in T-cell activity
  • Increase of 50% in interleukin-2
  • Increase of 22% to 37% in natural killer cell number
  • Increase of 45% in natural killer cell activity.