1. How do I start?
2. What are the guidelines to remain mindful of?
3. The fuel is the food, but how you eat that fuel is more important
4. How does Leptin tie into the quilt survivability index?
I have been asked by many to put a short post out about how I reverse
Leptin resistance in my own clinic for my patients. After reading all
of the comments left here, at MDA, and on Jimmy Moore’s forum, I decided
that it was a good idea.
1. First make sure you really are Leptin resistant (LR) to begin with.
The easiest way to do this if you are heavy is to look in the mirror.
If you’re overweight you definitely are Leptin resistant. If you still
have a large appetite and crave carbohydrates, especially at night,
these are also signs that you are likely Leptin resistant. If you are
fit or in decent shape and not sure based upon the above symptoms, I
would tell you to go get a blood test and check your reverse T3. It
will be elevated. I also recommend simultaneously checking a salivary
cortisol level. With LR, you will always see higher cortisol levels
later in the day.
2. To regain Leptin Sensitivity (LS) follow a strict
Paleolithic diet as outlined in The Paleo Solution by Robb Wolf or The
Primal Blueprint by Mark Sisson.
The type of fuel you eat is important in eliminating the foods that
cause Leptin receptors to become nonfunctional. These two books clearly
outline a solid reference point to achieve this.
A. Try to eat as soon as possible upon rising in the AM, ideally within
30 minutes of waking. Make sure that breakfast has little to no carbs
(less than 50 grams), and has a lot of protein and fat. I use as a
general rule 50-75 grams of protein with most patients. Some patients
can use less and some need more. The key point of knowing how much is
right for you is your hunger later in the day. If you remain ravenous
throughout the day, you need to eat more protein in the AM. If you can
hold off eating until dinner you probably are at homeostasis for you.
If you can skip both meals you likely are overdoing it at breakfast. As
for sources, I suggest pastured or organic eggs first, served with left
over dinner scraps of grass fed meats, poultry, or fish. A third
option, although less ideal, would be whey protein or protein shakes.
B. Try to limit carb intake to 25 grams if you are overweight by more
than 30 lbs. If you are fit and have a small amount of weight to lose,
(less than 30 lbs.) you can titrate up your carb loads. Even then, I do
not advocate potatoes or rice as some Paleo diets allow for. You will
be able to eat them eventually, but try to avoid starches until you have
mastered your cravings and hunger. Do not count calories; it is not
needed at this point. Any time I eat carbs I use liberal amounts of
butter, heavy cream, coconut or palm oil. I do not recommend other oils
initially such as olive oils or industrial seed oils. I would also
avoid nut oils at the initial stages. My personal favorite is coconut
oil because of the great metabolic effects of MCT, and how it helps heal
the guts of LR folks.
3. How you eat your fuel is MORE IMPORTANT than any other factor, including the food itself.
A. Never snack at all. This is meant initially and forever. Snacking
completely stresses the liver’s metabolism and is just not recommended.
Your liver needs to re-learn how to use gluconeogenesis normally again
when you are asleep and awake. Snacking just destroys the timing and
circadian clocks that work in unison with Leptin.
B. Try to eat three meals a day initially; but as your hunger and cravings fade you can adapt to two a day.
C. Try to eat breakfast as early as possible from rising.
D. Do not work out before or after breakfast.
E. Try to allow 4-5 hours between dinners and sleep time.
F. If you decide to incorporate working out, do it after 5 PM.
G. Within an hour of sunset try to make your surroundings as dark as possible.
H. If you have trouble falling asleep I suggest 3-5 minutes of body
weight exercises right before bed (pushups or air squats are fine, but
avoid this if your PM cortisol is high).
I. If you’re inclined to, try becoming mindful when you first lay
down. I use transcendental meditation techniques to help me clear my
mind and concentrate on improving my thinking. (Optional; but this is
awesome if your PM cortisol is high).
4. Most people will notice a change in their cravings and hunger within 4-6 weeks.
Other changes I advise of my patients, is to supplement with
prescription grade fish oils. The dose depends upon their HS CRP and
salivary cortisol levels.
5. Signs that you are becoming Leptin Sensitive (LS) again
A. Men will notice quick weight loss.
B. Women will notice mood changes first (calmer/sleepy) and their sleep
will improve. Their clothes will fit differently but weight may not
change drastically initially because of effects on the pituitary. This
will change too if they continue moving forward.
C. You will notice a change in your sweating pattern.
D. You will notice you have better recovery from exercise and your energy levels seem to have risen.
E. Your hunger is gone and so are your cravings.
F. When you awaken you will feel very refreshed like you slept well.
Generally when the signs are all present, I then really push HIIT exercise with heavy weights.
6. (QUILT SURVIVABILITY) = (Total Energy – Growth and immunity expense)
X (RESOURCES) X (efficiency) X (awareness of our environment).
Stated in levee form where:
Cell longevity = LS – IGF-1 + immunity X Food Quality X leakiness of Mitochondria X environmental cues
Note: I've been considering following one these two dietary protocols: Paleo Diet or Primal Blueprint? I am leaning towards Primal Blueprint. Reason: primal Blueprint allows for good fats such as Coconut oil, and butter. Yes, butter, maybe Paula Deen is onto something, Interestingly enough, The Paleo Diet allows for diet soda and Canola oil, two items on the food list which I do not ingest nor stock in my kitchen pantry - and that is my choice and opinion only. I personally use extra virgin olive oil, small amounts of flax seed oil, coconut oil for baking and animal fats (lard or butter) for frying on occasion.